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dc.contributor.editorCohmer, Seanen_US
dc.contributor.editorBaranski, Marcien_US
dc.creatorTantibanchachai, Chanapaen_US
dc.date.accessioned2014-07-20T21:23:03Z
dc.date.available2014-07-20T21:23:03Z
dc.date.created2014-07-20en_US
dc.date.issued2014-07-20
dc.identifier.urihttp://hdl.handle.net/10776/8040
dc.description.abstractIsotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal abnormalities including cleft lips, ear and eye defects, and mental retardation. Isotretinoin is commonly called by its trade name Accutane, and it's a chemical compound derived from vitamin A, or retinoic acid. Doctors prescribe isotretinoin to treat severe acne. For pregnant women, too much vitamin A or isotretinoin can also cause greater than normal rates of stillbirths and fetal disintegrations after the ninth week of gestation. Women who use isotretinoin during the first trimester of their pregnancies, even in small amounts, risk defects to their fetuses such as external ear malformations, cleft palates, undersized jaws (micrognathia), a variety of heart defects, buildups of fluids inside the skulls that leads to brain swelling (hydrocephalus), small heads and brains (microcephaly), and mental retardation.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoengen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectConcepten_US
dc.subject.lcshTeratogenic agentsen_US
dc.subject.lcshVitamin Aen_US
dc.subject.lcshIsotretinoinen_US
dc.subject.lcshAbnormalities, Humanen_US
dc.subject.meshIsotretinoinen_US
dc.subject.meshTeratogensen_US
dc.titleIsotretinoin (Accutane) as a Teratogenen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoReproductionen_US
dc.subject.embryoDisordersen_US
dc.subject.tagBirth defectsen_US
dc.subject.tagAccutaneen_US
dc.subject.tagHoffman-La Rocheen_US
dc.description.typeArticlesen_US


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