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dc.contributor.editorTantibanchachai, Chanapaen_US
dc.creatorDrago, Maryen_US
dc.date.accessioned2014-03-14T16:07:21Z
dc.date.available2014-03-14T16:07:21Z
dc.date.created2014-03-14en_US
dc.date.issued2014-03-14
dc.identifier.urihttp://hdl.handle.net/10776/7644
dc.description.abstractFrank Rattray Lillie's research on freemartins from 1914 to 1920 in the US led to the theory that hormones partly caused for sex differentiation in mammals. Although sometimes applied to sheep, goats, and pigs, the term freemartin most often refers to a sterile cow that has external female genitalia and internal male gonads and was born with a normal male twin. Lillie theorized that a freemartin is a genetic female whose process of sexual development from an undifferentiated zygote was suppressed or antagonized by her twin's release of male hormones via their shared blood circulation in utero. Despite publications of similar findings by physician Julius Tandler in Vienna, Austria, in 1910 and physician Karl Keller in Wiesensteig, Germany in 1916 prior to Lillie's research, Lillie often receives credit for the hormonal theory of sex differentiation in the freemartin. Lillie's study of freemartins, and the subsequent research by graduate students in Lillie's laboratory at the University of Chicago in Chicago, Illinois, prompted many embryologists to research sex differentiation and hermaphroditism in mammals.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoengen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectExperimenten_US
dc.subject.lcshLillie, Frank Rattray, 1870-1947en_US
dc.subject.lcshIntersexuality in animalsen_US
dc.subject.meshFreemartinismen_US
dc.subject.meshHormonesen_US
dc.titleFrank Rattray Lillie's Study of Freemartins (1914-1920)en_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoExperimentsen_US
dc.subject.tagsex hormonesen_US
dc.description.typeArticlesen_US


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