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dc.creatorO'Connor, Kathleenen_US
dc.creatorO'Neil, Ericaen_US
dc.date.accessioned2013-03-18T23:34:16Z
dc.date.available2013-03-18T23:34:16Z
dc.date.created2012-12-19en_US
dc.date.issued2013-03-18
dc.identifier.otherembryo:129154en_US
dc.identifier.urihttp://hdl.handle.net/10776/4207
dc.description.abstractIn a clinical trial from 1969 to 1972, Sir Graham Collingwood Liggins and Ross Howie showed that if doctors treat pregnant women with corticosteroids before those women deliver prematurely, then those women's infants have fewer cases of respiratory distress syndrome than do similarly premature infants of women not treated with corticosteroids. Prior to the study, premature infants born before 32 weeks of gestation often died of respiratory distress syndrome, or the inability to inflate immature lungs. Liggins and Howie, then both at the University of Auckland in Auckland, New Zealand, published their results in A Controlled Trial of Antepartum Glucorticoid Treatment for Prevention of the Respiratory Distress Syndrome in Premature Infants in 1972. The study built on experiments Liggins had earlier conducted with sheep. Liggins' corticosteroid experiments changed the way doctors treated pregnant women experiencing preterm labors, and they improved the life expectancy of prematurely born infants.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoengen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectExperimenten_US
dc.subject.lcshLiggins, G. C.en_US
dc.subject.lcshLiggins, G. C.
dc.subject.lcshAdrenocortical hormones
dc.subject.lcshpregnancy
dc.subject.lcshRespiratory distress syndrome
dc.subject.lcshPremature infants
dc.subject.lcshPremature labor
dc.subject.lcshSheep
dc.subject.lcshFetus
dc.subject.lcshFetal development
dc.subject.lcshBirth
dc.subject.meshFemale Urogenital Diseases and Pregnancy Complications--Pregnancy Complications--Obstetric Labor Complications--Obstetric Labor, Premature--Premature Birthen_US
dc.titleCorticosteroids' Effect on Fetal Lung Maturation (1972), by Sir Graham Collingwood Liggins and Ross Howieen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (http://creativecommons.org/licenses/by-nc-sa/3.0/)en_US
dc.subject.embryoExperimentsen_US
dc.subject.tagFetusen_US
dc.subject.tagHormonesen_US
dc.description.typeArticlesen_US
dc.date.createdstandard2012-12-19en_US


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