Show simple item record

dc.creatorJiang, Lijingen_US
dc.date.accessioned2012-05-25T15:44:02Z
dc.date.available2012-05-25T15:44:02Z
dc.date.created2011-04-27en_US
dc.date.issued2012-05-25
dc.identifier.otherembryo:128386en_US
dc.identifier.urihttp://hdl.handle.net/10776/2275
dc.description.abstractRichard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist Carroll M. Williams. Lockshin and Williams used this doctoral research as the basis for five articles, with the main title "Programmed Cell Death," that were published between 1964 and 1965 in the Journal of Insect Physiology. These articles examine the cytological processes, neuronal and endocrinal controls, and the influence of drugs on the mechanism of cell death observed in pupal muscle structures of the American silkmoth. Those muscle structures disappeared right after the completion of adult development. Several scientists have credited this series of articles as introducing the now standard term "programmed cell death." Among the five articles, "Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths" (abbreviated hereafter as "Endocrine Potentiation") was published first and has been cited the most often. The article suggests that the endocrinal conditions at the beginning of the adult development are necessary, but not sufficient, for precisely scheduling three weeks later the cell death activities in the pupal intersegmental muscles of American silkmoths. The research was among the first to attempt to pinpoint the role of hormones in regulating cell death, a process integral to development.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoengen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsen_US
dc.rights© Arizona Board of Regentsen_US
dc.subjectLiteratureen_US
dc.title"Programmed Cell Death-II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths" (1964), by Richard A. Lockshin and Carroll M. Williamsen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/
dc.subject.embryoExperimentsen_US
dc.subject.embryoPublicationsen_US
dc.subject.tagSilkwormsen_US
dc.subject.tagHormonesen_US
dc.subject.tagInsectsen_US
dc.description.typeArticlesen_US
dc.date.createdstandard2011-04-27


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record