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dc.creatorJiang, Lijingen_US
dc.date.accessioned2012-05-10T14:06:10Z
dc.date.available2012-05-10T14:06:10Z
dc.date.created2010-06-28en_US
dc.date.issued2012-05-10
dc.identifier.otherembryo:128101en_US
dc.identifier.urihttp://hdl.handle.net/10776/2042
dc.description.abstractIn the 1910s, Alexis Carrel, a French surgeon and biologist, concluded that cells are intrinsically immortal. His claim was based on chick-heart tissue cultures in his laboratory that seemed to be able to proliferate forever. Carrel's ideas about cellular immortality convinced his many contemporaries that cells could be maintained indefinitely. In the 1960s, however, Carrel's thesis about cell immortality was put into question by the discovery that human diploid cells can only proliferate for a finite period. As it was gradually recognized that chick cells only have a finite proliferative life span in vitro as well, historians and scientists alike attempted to identify experimental errors that could have led to the extremely long life of Carrel's "immortal" chick-heart tissue cultures. Those reassessments not only point out potential experimental mistakes in pioneer tissue culture work in the early twentieth century, but are also relevant to current discussions about the different life spans of germ line cells, embryonic and adult stem cells, normal somatic cells, and cancer cells.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoengen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rights© Arizona Board of Regentsen_US
dc.subjectContexten_US
dc.subject.lcshCarrel, Alexis, 1873-1944en_US
dc.subject.meshTissue Culture Techniquesen_US
dc.titleReassessment of Carrel's Immortal Tissue Culture Experimentsen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/
dc.subject.embryoProcessesen_US
dc.subject.embryoTheoriesen_US
dc.subject.tagTissue cultureen_US
dc.subject.tagChicksen_US
dc.description.typeArticlesen_US
dc.date.createdstandard2010-06-28


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