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dc.contributor.editorLienhard, Dina A.en_US
dc.creatorDarby, Alexisen_US
dc.creatorEllis, Briannaen_US
dc.date.accessioned2021-05-03T08:50:15Zen_US
dc.date.available2021-05-03T08:50:15Zen_US
dc.date.created2021-05-03en_US
dc.identifier.urihttps://hpsrepository.asu.edu/handle/10776/13260en_US
dc.description.abstractWilliam John Little was one of the first orthopedic surgeons to research congenital malformations and their causes in the nineteenth century and presented preliminary research on a condition modernly known as cerebral palsy, a condition of varying severity that affects a person’s ability to move. Little worked throughout the United Kingdom for the majority of the time he practiced medicine, and eventually founded one of the first orthopedic infirmaries, the Royal Orthopedic Hospital in London, England. Throughout his career, Little studied congenital malformations, which are medical conditions inherited before birth, as well as how certain medical circumstances during delivery affect the neonate. In 1861, he described a condition with motor, behavioral, and cognitive irregularities in neonates, linked with oxygen deprivation during birth. Little’s research on that condition, originally called Little’s disease, and modernly, spastic cerebral palsy, was one of the first accounts of cerebral palsy in infants.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoen_USen_US
dc.language.isoen_USen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectPeopleen_US
dc.subject.lcshBirth injuries--Complicationsen_US
dc.subject.lcshBirth injuries--Complications and sequelaeen_US
dc.subject.lcshLittle's diseaseen_US
dc.subject.lcshParalysis, Cerebralen_US
dc.subject.lcshCerebral palsy--Patientsen_US
dc.subject.lcshCerebral paralysisen_US
dc.subject.lcshMuscle spasticityen_US
dc.subject.lcshSpasticityen_US
dc.subject.lcshSpasticity--Diagnosisen_US
dc.subject.lcshAbnormalities, Humanen_US
dc.subject.lcshCongenital abnormalitiesen_US
dc.subject.lcshBirth defectsen_US
dc.subject.lcshAnomalies, Congenitalen_US
dc.subject.lcshNervous system--Abnormalitiesen_US
dc.subject.lcshBrain--Abnormalitiesen_US
dc.subject.meshCerebral Palsyen_US
dc.subject.meshCP (Cerebral Palsy)en_US
dc.subject.meshCerebral Palsy, Mixeden_US
dc.subject.meshSpastic diplegia cerebral palsyen_US
dc.subject.meshCerebral palsy, spastic, diplegicen_US
dc.subject.meshCerebral Palsy, Spastic Quadriplegic, 1en_US
dc.subject.meshCerebral Palsy, Ataxic, Autosomal Recessiveen_US
dc.subject.meshAtaxic Cerebral Palsyen_US
dc.subject.meshMicrophthalmia and mental deficiencyen_US
dc.subject.meshCerebral Palsy, Athetoiden_US
dc.subject.meshCongenital Defectsen_US
dc.subject.meshParturitionen_US
dc.subject.meshHypoxiaen_US
dc.titleWilliam John Little (1810–1894)en_US
dc.typeArticleen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoPeopleen_US
dc.subject.embryoDisordersen_US
dc.subject.tagLittle's diseaseen_US
dc.subject.tagcongenital malformationsen_US
dc.subject.tagspastic diplegiaen_US
dc.description.typeArticlesen_US


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