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dc.contributor.editorDarby, Alexisen_US
dc.creatorSchnebly, Risa Aria
dc.date.accessioned2020-12-10T07:12:16Z
dc.date.available2020-12-10T07:12:16Z
dc.date.created2020-12-10
dc.identifier.urihttps://hpsrepository.asu.edu/handle/10776/13199
dc.description.abstractMultiplex Automated Genome Engineering, or MAGE, is a genome editing technique that enables scientists to quickly edit an organism’s DNA to produce multiple changes across the genome. In 2009, two genetic researchers at the Wyss Institute at Harvard Medical School in Boston, Massachusetts, Harris Wang and George Church, developed the technology during a time when researchers could only edit one site in an organism’s genome at a time. Wang and Church called MAGE a form of accelerated evolution because it creates different cells with many variations of the same original genome over multiple generations. MAGE made genome editing much faster, cheaper, and easier for genetic researchers to create organisms with novel functions that they can use for a variety of purposes, such as making chemicals and medicine, developing biofuels, or further studying and understanding the genes that can cause harmful mutations in humans.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoen_USen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectTechnologyen_US
dc.subject.lcshGene splicingen_US
dc.subject.lcshGenetic engineering industryen_US
dc.subject.lcshGenetic engineeringen_US
dc.subject.lcshGenetic epidemiologyen_US
dc.subject.lcshGene librariesen_US
dc.subject.lcshImmunogeneticsen_US
dc.subject.meshGenetic Engineeringen_US
dc.subject.meshGenetic Interventionen_US
dc.subject.meshGenetically Engineered Organismsen_US
dc.subject.meshGenetically Modified Organismsen_US
dc.subject.meshGenomic Libraryen_US
dc.subject.meshGenomeen_US
dc.subject.meshBacterial Genomesen_US
dc.subject.meshHuman Genomeen_US
dc.titleMultiplex Automated Genome Engineering (MAGE)en_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoTechnologiesen_US
dc.subject.embryoProcessesen_US
dc.subject.taggenome editingen_US
dc.subject.tagGMOsen_US
dc.subject.tagde-extinctionen_US
dc.description.typeArticlesen_US


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