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dc.contributor.editorDarby, Alexisen_US
dc.creatorSchnebly, Risa
dc.date.accessioned2020-10-01T21:38:50Z
dc.date.available2020-10-01T21:38:50Z
dc.date.created2020-10-01
dc.identifier.urihttps://hpsrepository.asu.edu/handle/10776/13170
dc.description.abstractIn 1972, David Whittingham, Stanley Leibo, and Peter Mazur published the paper, “Survival of Mouse Embryos Frozen to -196 ° and -269 °C,” hereafter, “Survival of Mouse Embryos,” in the journal Science. The study marked one of the first times that researchers had successfully cryopreserved, or preserved and stored by freezing, a mammalian embryo and later transferred that embryo to a live mouse who gave birth to viable offspring. Previously, scientists had only been successful cryopreserving single cells, like red blood cells. Mammalian embryos, on the other hand, were more difficult to cryopreserve because they are more complex and therefore more easily weakened or destroyed by the formation of ice within its cells. Whittingham, Leibo, and Mazur’s work provided a successful model for mammalian embryo cryopreservation, a technology that later expanded to cryopreserve more complex embryos, such as human embryos.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoen_USen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectLiteratureen_US
dc.subject.lcshCryopreservation of organs, tissues, etcen_US
dc.subject.lcshCultures (Biology)--Cryopreservationen_US
dc.subject.lcshCells--Cryopreservationen_US
dc.subject.lcshFreezing points of solutionsen_US
dc.subject.lcshCryobiologyen_US
dc.subject.meshCryonic Suspensionen_US
dc.subject.meshCryofixationen_US
dc.subject.meshCryopreservationen_US
dc.subject.meshHistorical Aspectsen_US
dc.subject.meshOsmosisen_US
dc.title“Survival of Mouse Embryos Frozen to -196 ° and -269 °C” (1972), by David Whittingham, Stanley Leibo, and Peter Mazuren_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoExperimentsen_US
dc.subject.embryoPublicationsen_US
dc.subject.tagcryopreservationen_US
dc.subject.tagfrozen embryosen_US
dc.description.typeArticlesen_US


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