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dc.contributor.editorZietal, Bianca E.en_US
dc.creatorGarcia, Dasia
dc.date.accessioned2017-05-12T18:39:19Z
dc.date.available2017-05-12T18:39:19Z
dc.date.created2017-05-12
dc.identifier.urihttp://hdl.handle.net/10776/11499
dc.description.abstractScientists use cerebral organoids, which are artificially produced miniature organs that represent embryonic or fetal brains and have many properties similar to them, to help them study developmental disorders like microcephaly. In human embryos, cerebral tissue in the form of neuroectoderm appears within the first nine weeks of human development, and it gives rise to the brain and spinal cord. In the twenty-first century, Juergen Knoblich and Madeleine Lancaster at the Institute of Molecular Biotechnology in Vienna, Austria, grew cerebral organoids from pluripotent stem cells as a model to study developmental disorders in embryonic and fetal brains. One such disorder is microcephaly, a condition in which brain size and the number of neurons in the brain are abnormally small. Scientists use cerebral organoids, which they've grown in labs, because they provide a manipulable model for studying how neural cells migrate during development, the timing of neural development, and how genetic errors can result in developmental disorders.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoen_USen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectTechnologyen_US
dc.subject.lcshMicrocephalyen_US
dc.subject.lcshBrainen_US
dc.subject.lcshNeuronsen_US
dc.subject.lcshBrain--Diseases--Animal modelsen_US
dc.subject.lcshStem cells--Researchen_US
dc.titleCerebral Organoid as a Model System in the Study of Microcephalyen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoTechnologiesen_US
dc.description.typeArticlesen_US
dc.date.createdstandard2017-05-12en_US


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