Show simple item record

dc.contributor.editorTurriziani Colonna, Federicaen_US
dc.contributor.editorGleason, Kevin M.en_US
dc.creatorZhu, Meilin
dc.date.accessioned2017-03-30T20:18:20Z
dc.date.available2017-03-30T20:18:20Z
dc.date.created2017-03-30
dc.identifier.urihttp://hdl.handle.net/10776/11460
dc.description.abstractThe Guthrie test, also called the PKU test, is a diagnostic tool to test infants for phenylketonuria a few days after birth. To administer the Guthrie test, doctors use Guthrie cards to collect capillary blood from an infant’s heel, and the cards are saved for later testing. Robert Guthrie invented the test in 1962 in Buffalo, New York. Phenylketonuria (PKU) is a congenital birth abnormality in which toxic levels of the amino acid phenylalanine build up in the blood, a process that affects the brains in untreated infants. Guthrie’s test detects phenylalanine in the blood of newborns, enabling for early diagnosis of PKU. Early diagnoses of PKU prevent the development of mental disabilities in the thousands of individuals affected each year.en_US
dc.format.mediumtext/xhtmlen_US
dc.language.isoen_USen_US
dc.publisherArizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia.en_US
dc.relation.ispartofEmbryo Project Encyclopediaen_US
dc.rightsCopyright Arizona Board of Regentsen_US
dc.subjectTechnologyen_US
dc.subject.lcshGuthrie, Robert, 1916-1995en_US
dc.subject.lcshAssociation for Retarded Citizens of the United Statesen_US
dc.subject.lcshFolder (United States. Children's Bureau)en_US
dc.subject.lcshMiles Laboratories. Ames Divisionen_US
dc.subject.lcshAmes Companyen_US
dc.subject.lcshUnited States, Department of Health and Human Servicesen_US
dc.subject.lcshAssociation for the Aid of Crippled Childrenen_US
dc.subject.lcshPhenylketonuriaen_US
dc.subject.lcshMental retardationen_US
dc.subject.lcshAmino acids--Metabolism--Disordersen_US
dc.subject.lcshBlood testingen_US
dc.subject.lcshTandem mass spectrometryen_US
dc.subject.meshDeficiency Disease, Phenylalanine Hydroxylaseen_US
dc.titleThe Guthrie Test for Early Diagnosis of Phenylketonuriaen_US
dc.typeTexten_US
dc.rights.licenseLicensed as Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported (CC BY-NC-SA 3.0) http://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.subject.embryoTechnologiesen_US
dc.subject.tagNewborn Screeningen_US
dc.description.typeArticlesen_US
dc.date.createdstandard2017-03-30en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record