The Developmental Capacity of Nuclei taken from Intestinal Epithelium Cells of Feeding Tadpoles by J. B. Gurdon (1962)
The Developmental Capacity of Nuclei taken from Intestinal Epithelium Cells of Feeding Tadpoles describes a series of experiments by researcher John Bertrand Gurdon in 1962 at the University of Oxford in Oxford, England. In the experiment, Gurdon conducted nuclear transplantation, or cloning, of differentiated cells, or cells that have already specialized to become one cell type or another, in tadpoles. Gurdon's experiment showed that differentiated adult cells could be induced to an undifferentiated state, where they could once again become multiple cell types. Gurdon's experiment disproved the theory that differentiated cells could not be undifferentiated or dedifferentiated into a new type of differentiated cell. Gurdon's experiment demonstrated nuclear transplantation, also called cloning, using differentiated cells.